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Bendamustine-bendit

NATCO PHARMA LIMITED (INDIA)

Bendamustine-bendit


Bendamustine” is the Drug / Molecule content in “Bendit”. Bendamustine belongs to a class of medication known as alkylating agents. Alkylating agents are most active in the resting phase of the cell-cycle.  There are several types of alkylating agents. Bendamustine is a nitrogen mustard derivative and is active against resting as well as dividing cells.


Indication

Bendamustine is used to treat Chronic Lymphocytic Leukemia (CLL) that is a type of cancer of the white blood cells. It is also indicated for a type of Non-Hodgkin’s Lymphoma.

Note

SIDE EFFECTS :

  • Low blood counts : white and red blood cells and platelets may temporarily decrease
  • Increase in bilirubin levels.
  • Common side effects include: Infusion reaction (chills, fever, itching, rash), Fever, Nausea, Vomiting, Fatigue, Diarrhea, Rash.

INTERACTIONS :

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Especially tell your doctor if you take:

  • Medications that block the enzyme CYP1A2 such as Zileuton, Amiodarone, Mexiletine, Propafenone, Verapamil, Cimetidine, Famotidine, Birth control pills, Acyclovir, Ticlopidine, Ciprofloxacin and Fluvoxamine.
  • Medications that increase the activity of the enzyme CYP1A2 such as Montelukast, Phentoin, Omeprazole, Phenobarbital.
  • Cigarette smoking may decrease the effectiveness of Bendamustine

OVERDOSE :

If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if an overdose is suspected, seek emergency medical attention.

 

Precaution

  • Bendamustine is a prescription drug and should be used under proper medical guidance and advice.
  • Bendamustine may cause Myelosuppression & lead to some infections.
  • Bendamustine may lead to renal failure and anaphylactic reaction.
  • Use in pregnancy should be avoided.

Updated On Oct 17, 2019 by Admin

Strength

100 mg

Packing

Vial

Storage

Store at a temperature not exceeding 30 C. Retain in original package until time of use to protect from light.



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