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Etoposide-etosid

CIPLA LTD. (INDIA)

Etoposide-etosid


“Etoposide” is the drug / molecule content in "Etosid". Etoposide is an inhibitor of the enzyme topoisomerase II. It is a derivative of podophyllotoxin (plant alkaloid) that inhibits DNA synthesis resulting in the arrest of the cell cycle.


Indication

Etoposide is used as a form of chemotherapy for malignancies such as Ewing's sarcoma, Lung cancer, Testicular cancer, Lymphoma, Non-Lymphocytic Leukemia, and Glioblastomamultiforme. It is also sometimes used in a conditioning regimen prior to a bone marrow or blood stem cell transplant.

Note

SIDE EFFECTS :

  • Common side effects include Low Blood Cell counts, Vomiting, Loss of appetite, Diarrhea, Hair loss and fever.
  • Other severe side effects include allergic reactions and low blood pressure.

 INTERACTIONS :

  • Etoposide interact with other drug include Abametapir, Erdafitinib, apripitant, atazanavir, Axitinib, Bosentan, Cimetidine, Dexamethasone, Erythromicin, Hydroxyurea, Isoniazide, Ketoconazole, Lapatinib, Nilotinib etc.

OVERDOSE :

  • Do not use more than prescribed dose.
  • Patients who have received doses higher than those recommended should be carefully monitored.
  • Do not take extra dose to make up for the missed dose.

Precaution

  • Etosid is a prescription drug and should be used under proper medical guidance and advice.
  • Caution should be exercised in patients with history of kidney disease, bone marrow depression, infections, or blood disorder, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. 

Updated On Oct 25, 2019 by Admin

Strength

50 mg & 100 mg

Packing

1 X 4 Capsule (50 mg) & Single dose vial (100 mg)

Storage

Store at room Temperature (25°C).



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