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Daclatasvir-natdac

NATCO PHARMA LIMITED (INDIA)

Daclatasvir-natdac


“Daclatasvir” is the Drug / Molecule content in “Natdac”. Daclatasvir is used for the treatment of patients with chronic Hepatitis C virus (HCV). Daclatasvir inhibits the Hepatitis C Virus (HCV) nonstructural protein; by targeting two steps of the viral replication process, enabling rapid decline of HCV RNA.


Indication

Daclatasvir is used for treatment of patients with chronic Hepatitis C .

Note

SIDE EFFECTS :

  • Serious risk of bradycardia when Daclatasvir is used with Sofosbuvir and Amiodarone.
  • Common side effects include:  Headache, Hemolytic Anemia, Nausea, Fatigue, Diarrhea.

INTERACTIONS :

  • Some common drugs that are strong CYP3A inducers include Dexamethasone, Phenytoin, Carbamazepine, Rifampin,
  • When taking Daclatasvir with  Non-nucleoside reverse transcriptase inhibitors, the dose of Daclatasvir is increased to overcome CYP3A induction.
  • The dose for Daclatasvir should be lowered when taking with antifungals, such as Ketoconazole.
  • Concurrent use with Amiodarone, Sofosbuvir and Daclatasvir has may result in an increased risk for serious slowing of the heart rate.

OVERDOSE :

  • Do not use more than prescribed dose.
  • If you suspect you may have overdosed, call your healthcare provider.
  • Do not take extra dose to make up for the missed dose.

 

 

Precaution

  • Cases of severe bradycardia and heart block have been observed when used in combination with sofosbuvir with or without other drugs that lower heart rate.
  • Daclatasvir should not be used during pregnancy or in women of childbearing potential not using contraception.

 

Updated On Oct 17, 2019 by Admin

Strength

30 mg & 60 mg

Packing

1 X 28 Tablets (Plastic Container)

Storage

Store at room Temperature , protected from sunlight.



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