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Sofosbuvir & velpatasvir-velpanat

NATCO PHARMA LIMITED (INDIA)

Sofosbuvir & velpatasvir-velpanat


“Sofosbuvir & Velpatasvir” are the Drugs / Molecules content in “Velpanat.

Sofosbuvir & Velpatasvir has high overall cure rates of 99% for GT2 patients and 95% for GT3 patients. Sofosbuvir & Velpatasvir was also found to be highly effective in patients with GT1, GT4, GT5 and GT6, with overall cure rates ranging from 97–100%.


Indication

Sofosbuvir & Velpatasvir are helpful for treatment of all Hepatitis C adults who are suffering from genotype 1-6 chronic hepatitis C virus.

Note

SIDE EFFECTS :

  • Common side effects include muscle pains, headache, nausea, rash, diarrhea, insomnia and cough.
  • More severe reactions are connected with allergic reactions to the medications and cardiovascular problems.

INTERACTIONS :

  • For the HIV combination Efavirenz / Emtricitabine / Tenofovir, which reduces the area under the curve (AUC) of Velpatasvir by about 50%, and the CYP3A4 and Pgp inducer Rifampicin, which reduces its AUC by about 80%, rendering it likely ineffective.
  • Digoxin is eliminated by Pgp; its AUC is increased by about 30% in combination with Velpatasvir and Sofosbuvir.
  • Substances that reduce gastric acid, such as Antacids, H2 blockers, and Proton pump inhibitors, reduce Velpatasvir AUC by 20–40%.

OVERDOSE :

  • Do not use more than prescribed dose.
  • If you suspect you may have overdosed, call your healthcare provider.
  • Do not take extra dose to make up for the missed dose.

 

Precaution

  • Sofosbuvir & Velpatasvir are the prescription drug and should be used under proper medical guidance and advice.
  • Caution should be exercised in patients with history of stomach problem, liver, kidney, or heart disease during pregnancy and breastfeeding.

Updated On Oct 16, 2019 by Admin

Strength

400 mg Sofosbuvir / 100 mg Velpatasvir

Packing

1 X 28 Tablets (Plastic Container)

Storage

Store at room temperature.



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